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【分享】Ensuring the purity of platinum-cured silicone- l! ?% L7 y5 C+ F9 Q0 m( F
摘要：Platinum-cured silicone tubing plays a key role in manufacturing drugs and medicines in validated E- ^! c( [7 K" V( |/ E
and non-validated processes in the pharmaceutical/biopharmaceutical industry.; k7 T8 p$ u0 |+ j4 J* U
Though platinum-cured tubing is industry standard, platinum curing, in itself, does not guarantee
i- X6 s# A+ }( Za high level of tubing purity with low/safe levels of extractables. Watson-Marlow1 v2 Y6 A& j, R4 G- K( |" U7 c
achieves ultimate purity by driving off cytotoxic extractables through post-curing, a process% O" H7 S( i# I$ _
step many tubing manufacturers ignore. Some producers believe post-curing is not necessary,
' k: }. \8 q- e0 Mclaiming that the naturally lower extractables of platinum-cured tubing (compared with) H5 D- F/ g2 U7 [
peroxide-cured silicone) is sufficient. This bulletin outlines the importance of post-curing for# w; m! G( I+ |' E/ l
the high-purity pharmaceutical/biopharmaceutical market, describing the key effects on the
: f4 g! e N" h% m& ^. |tubing and the key benefits for the user. |
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发表于 2010-9-3 08:12:39
