Design and Optimization in organic synthesis(elsevier经典)

fenglianxiang

Data Handling in Science and Technology---Vol 24
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' Z- \4 W7 P# M. L4 vDesign and Optimization in Organic Synthesis
' u; P+ D8 T, }& T  }5 ?By Rolf Carlson and Johan Carlson
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+ U) s" \4 x, y5 }' a7 vContents
Chapter 1   Introduction: Strategies on different levels in organic synthesis.
" F, ~% B1 M/ \- b  I5 I/ P$ G" [Chapter 2   Experimental study of reaction conditions. Initial remarks.
: j5 A, D: l9 r7 ^! `- hChapter 3   Models as tools.
Chapter 4   General outline of screening experiments.
6 F6 U  C/ L3 f* [# L: }Chapter 5   Two-level factorial designs.
( J7 m$ R4 k& F& v5 P6 ^1 p6 z! gChapter 6   Two-level fractional factorial designs.
+ b  v4 m- s7 VChapter 7   Other designs for screening experiments.
Chapter 8   Summary of screening experiments.
; k" \) `# q+ {9 N$ u, W- MChapter 9   Optimisation.
Chapter 10  Steepest ascent.
Chapter 11  Simplex methods.
" ]$ l" {: |9 qChapter 12  Response surface methods.
% `4 u  G, z7 ]- d$ i' [' MChapter 13  Reaction kinetics by sequential response surface modelling.
Chapter 14  Summary of strategies for exploring the experimental space.
0 V3 z( d) G& j: ^4 IChapter 15  The reaction space.
Chapter 16  Principal properties.
5 W" j4 p! ]+ I0 cChapter 17  Strategies for the selection of test systems.
Chapter 18  Quantitative relations: Observed responses and experimental variations.
2 q, A0 ]) v; A0 B$ I: MChapter 19  Exploring discrete variations: Near-orthogonal experiments by singular value.
Chapter 20  Optimisation when there are several response variables.
Chapter 21  A method for determining suitable order of introducing reagents in "one-pot" procedures.
Chapter 22  Books, journals, and computer programs.
3 k% @, B2 D3 g: C' @" f7 {( CChapter 23  Concluding remarks.
* w2 Z* ?$ ?+ ]% I* k; k) f$ F$ dAppendix A  Matrix calculus.
Appendix B  Statistical tables
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& @. y% b) \# b[ 本帖最后由 fenglianxiang 于 2008-8-5 19:47 编辑 ]