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【分享】Ensuring the purity of platinum-cured silicone
$ F3 Q# p$ _/ a( c. C$ {% F摘要：Platinum-cured silicone tubing plays a key role in manufacturing drugs and medicines in validated
) X3 e( [( Z7 g4 u" hand non-validated processes in the pharmaceutical/biopharmaceutical industry.
5 M9 s ^: `' H( f+ Z5 HThough platinum-cured tubing is industry standard, platinum curing, in itself, does not guarantee: j# T* k0 e$ c0 y# [$ F
a high level of tubing purity with low/safe levels of extractables. Watson-Marlow6 j6 F" s7 \6 P1 G" ]
achieves ultimate purity by driving off cytotoxic extractables through post-curing, a process
1 k$ e" Q0 V, w) G; k) wstep many tubing manufacturers ignore. Some producers believe post-curing is not necessary,; }& d& H$ u: [. d& t
claiming that the naturally lower extractables of platinum-cured tubing (compared with
6 d% Q7 P. R9 Zperoxide-cured silicone) is sufficient. This bulletin outlines the importance of post-curing for
+ T4 i3 I* a4 a# t- x6 Cthe high-purity pharmaceutical/biopharmaceutical market, describing the key effects on the
5 o3 z; i* @/ Wtubing and the key benefits for the user. |
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发表于 2010-9-3 08:12:39
