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《The Cancer Handbook（癌症手册）》- g `$ ~5 @. _$ ]; ~ {
" u4 A+ N; ]5 M) w% s! I全书PDF格式，27.3M，高清晰，共13个压缩包。
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癌症手册提供关于癌症生物学和医学所有主要领域的科学和临床信息的综合概述，它与现有肿瘤学教程和参考资料的不同在于，癌症手册弥补了癌症分子生物学与临床诊断与治疗之间的差距。0 F! ^$ ]1 _& e9 M: L, q5 c
涉及广泛的学科-从基本细胞生物学到所有主要器官和组织的系统肿瘤学-癌症手册的内容组织成六个主要部分：
- a1 c5 n2 _$ P% G3 B! U5 h• 细胞和组织的分子基础0 k% |" d" ?: b3 f5 x4 R
• 癌症的原因和预防0 y9 R( Q `! L7 ]/ h% {
• 诊断显象和影像-引导的乾涉
+ _4 t$ }* c ?) W6 K, M' w9 A! P• 系统肿瘤学+ k& t. Y/ Q& Z- ~9 d( F
• 人类癌症的预诊断模式, F4 o# B% w5 S
• 人类癌症的治疗
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& n1 M K6 Z0 B对于医学和生命科学学生以及所有在癌症领域和相关生物医学领域工作的科学工作者、临床医师和研究工作者来说，这本书是不可缺少的资源。
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目录
! M/ s$ A! w: W- oSection A - The Molecular Basis of Cell and Tissue Organization
; O( H. j2 d$ P' Q5 B3 f/ ^1. Cell and Tissue Organisation4 E5 r5 v8 B3 { e& ?, l
2. Regulation of the Cell Cycle3 e" S4 A$ Q% I* {; R
3. Overview of Oncogenesis
) q5 d5 Z3 I9 y9 s8 p4. Inherited Predispositions to Cancer- i$ k! ^4 R4 W9 \8 v
5. DNA Viruses2 C6 j4 ?# E. ?( t8 N4 V. ]; F0 r
6. RNA Viruses ~( U# g ~4 |) {) F" b
7. Genetic Instability and DNA repair ` g7 E7 p2 X
8. Telomerase) P; y5 g% K) o7 U! u [
9. Apoptosis9 [! p$ Z+ s; l6 D
10. Signalling by steroid receptors# F- |4 B* R, Y
11. Signalling by cytokines2 s! X3 W5 C) f0 {2 ]; z! p
12. Signalling by tyrosine kinases& G- s9 U- x& F2 [* j' i
13. Signalling by TGF beta
: d: @9 L% W3 g! I7 C. r; H14. Wnt Signal Transduction' a/ {: O. z8 @4 X' J2 \, H! V! b
15. Extracellular Matrix: the networking solution
3 N2 e+ o; P% O16. Invasion and Metastasis
5 D8 r& r' \. j( F& Z" R17. Angiogenesis
: z! b: M( n& `$ T5 G( \18. Cell Proliferation in Carcinogenesis2 K. f. g, H& i0 a- o
Section B - The Causation and Prevention of Cancer# Q6 u; x9 S3 ?7 Y( Q8 K+ n
1. Identifying Cancer Causes through Epidemiology2 @* K o$ ^3 R& u7 M$ ?6 a/ v
2. Mechanisms of Chemical Carcinogenesis$ [/ Y0 o8 e0 I4 G/ `
3. The Formation of DNA Adducts
& C' f& ~3 d2 f1 S4 ~6 K4. Physical Causes of Cancer2 Z ?5 c% F0 t4 E7 a0 `6 l: ~0 L
5. Non-Genotoxic Causes of Cancer
; L& H* e p( Y- u i# P: p* _& V& ~6. Infectious Agents and Cancer1 V4 g5 Q$ b6 \
7. Short-term Testing for Genotoxicity5 v8 N8 u6 ]1 E- i
8. Cancer Bioassays for Pharmaceuticals a Regulatory Perspective
, g" E9 M1 h8 c9. Molecular Epidemiology of Cancer+ y2 e% G3 k! p& b: d
10. Dietary Genotoxins and Cancer
& N& Q# O+ ]. m2 E% Y11. Tobacco Use and Cancer; z# l6 I7 k X _5 i
12. Occupational Causes of Cancer% L3 b) Q) p: M( o0 C: x* Z/ {
13. Anti-Genotoxins and Cancer
# h. S3 Z6 R) Y14. Intervention and Chemoprevention) _+ M0 C {: Z0 v5 X
Section C - Diagnostic Imaging and Image-Guided Intervention
8 P0 ~) q7 s3 S& F3 kPart I- Imaging Modalities in Diagnosis and Monitoring( o4 `' [% r% E) b, e! S5 u" u* I+ T
1. Plain Film Radiography9 k5 D# q2 Y" D- H/ h3 h
2. Computed Tomography
6 s' d, S5 [: e9 w6 c. Q1 y3 w7 R3. Ultrasound
/ O! q7 J: y. n$ H4. Magnetic Resonance Imaging! \# `' ^2 L8 R" q4 Y7 i/ r
5. Nuclear Medicine Studies1 U) a6 M8 ]: o) X( I5 M% Y2 j9 c
6. Mammography7 l" v8 M) Z, a7 }
Part II - Diagnostic and Therapeutic Interventional Procedures3 x) ~& i! Q1 f
1. Percutaneous Biopsy2 e7 J' c- c# r5 L( I
2. Transcatheter Therapy! Q+ \ L/ }( k( A' B
3. Direct Percutaneous Tumour Therapy
- T {% w2 ]8 Y* ?# Y3 D2 a; ]' W& {8 RSection D - Systemic Oncology
5 O1 O n9 k0 G! Q2 K1. Introduction to the Diagnosis of Cancer
+ k* |: K' l0 S+ Y1 F X- P2. Skin
8 r/ Z; w( p% I( b. O3. Oral cavity & major and minor salivary glands* l: N, K: K/ m6 }$ Y* B* D4 Z
4. Respiratory tract
1 T/ u! X9 F, _3 A% E& e+ g1 R2 k# t5. Upper Gastrointestinal tract
- v+ c* N5 b' ^) N( }. s1 u a. D6. Lower gastrointestinal tract( L" s$ L: ^* w7 q
7. Liver, gall bladder and extrahepatic bile ducts.
6 F& @8 c$ v9 q( }; x8. Pancreas6 S( m! v4 P& f* ?' Y% [% [
9. Endocrine organs
! C- J% L1 [" G10. Breast
6 A$ M5 ~& P4 J11. Female reproductive system
* ], T/ u! s. U12. Urinary tract3 N- {8 ?; y( z5 R9 l3 K* X
13. Male reproductive system
; Z8 g( F8 l! v! {; `- t14. Lymph nodes, spleen and bone marrow. R. k) a9 S, [9 r7 l( s
15. Bones and joints.: x3 | ?! g7 V9 N+ \ ?
16. Soft Tissues
8 ]0 e, C1 \2 C5 F7 S17. Pleura and peritoneum( \5 L: g' C" y9 N' L e: A& o
18. Heart: o: w# |3 E3 m9 k! u5 c) L
19. Neuromuscular System0 G h6 t( _" U% a4 z# _7 _
20. Eye and ocular adnexa3 j5 X2 m% m4 n
21. Ear9 k. `3 t- s1 P l6 `
Appendum. Myeloid Leukemias and related Neoplasms4 ~. P+ d% f5 n8 t& J
Section E - Pre-clinical Models of Human Cancer, m7 T1 x" H7 ]+ o3 o
1. Advantages and limitations of models for human cancer2 D$ S2 y6 I, G# C* W$ e
2. Basic Tissue Culture
. ^2 e" _+ b/ r, U/ { P( Y3. Transgenic technology in the study of oncogenes and Tumor Suppressor Genes
2 V& H& G& U3 W% x4. Gene knockouts
) {! \7 c0 x% ]' s; E5. Human tumours in animal hosts' E' P4 p- [5 x' ]- _
6. Mammary tumour induction in animals as a model for human breast cancer
8 `: e/ Q( [. k7 M: I7. Mathematical models in cancer research) b k8 [# o3 P$ V+ ~) L5 r, w
8. Models for tumour growth and differentiation, |7 ]1 k4 A: J2 Q2 E s
9. Angiogenesis models+ }5 x7 q1 ~% E9 y- b1 m
10. Models for tumour cell adhesion and invasion
$ F& h, K/ Y% L/ J, n, a11. Tumour metastasis models! X; f3 S) u- N& m* c) N( [
12. Models for tumour cell-endothelial cell interactions* S% D8 A7 q# b
13. Modelling Tumor Tissue Interactives" V/ K$ F& r6 ^
14. Models for drug development and drug resistance
$ K' i$ ^( P5 H* L6 [15. Models for immunotherapy and cancer vaccines* r1 M1 ^: H3 a$ {. I
16. Gene therapy models
+ ?( O- C2 b) `3 W% Q! v17. Models for epithelial carcinomas" F; j7 }% z t: w" ]
18. Models for haematological malignancies
- a9 i" G3 K& n# a19. Models for melanomas and sarcomas
6 P0 Q( `* O' O1 w. @& b( x20. Models for CNS malignancies: H" A& R4 G! n) \* w9 y+ @' l9 t: J
21. Models for endocrine cancer
) C. s2 l6 E! c: j3 o4 ^2 i1 ?Section F - The Treatment of Human Cancer
. O6 ^3 C N; S* S$ }* d1. Mechanisms of action of cancer chemotherapeutic agents
3 l& m7 D0 P- x6 l( R2. Drug Resistance & Reversal7 V# y3 B0 z6 t: b: E
3. Molecular mechanisms of radiotherapy
6 y/ e ]9 P* B4 I$ L5 g# f4. Antibodies and recombinant cytokines
7 i5 B: {) K& b" E' o0 e3 Q5. Genetic and Cellular Vaccines
2 o& g0 o( V1 S& d4 h6. Differentiation Therapy; m- A% R' p" ]4 ?9 R: j9 ?( I, y
7. Chemoprevention
$ p" }8 m) Z" q& \8. Antisense & ribozyme therapy
" c, _0 U3 F+ U9. Hormonal Therapy
$ A$ L4 S# A5 x* c10. Antiangiogenic Therapy
. g3 p' j( H' f- x7 \0 k# N; \6 u11. Targeting the Extracellular Matrix0 H! I# [# | b
12. Growth Factor Receptor Blockade
. M6 L4 g% s1 A3 b' N13. Signal
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3 u: n5 |0 C" ?. z[ 本帖最后由 清风明月008 于 2007-8-12 10:32 编辑 ] |
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发表于 2007-8-12 09:52:34