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《The Cancer Handbook(癌症手册)》
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全书PDF格式,27.3M,高清晰,共13个压缩包。6 _- ?$ ]9 V; e9 d9 ]4 B) _
# z! ~; \9 ~8 H6 r癌症手册提供关于癌症生物学和医学所有主要领域的科学和临床信息的综合概述,它与现有肿瘤学教程和参考资料的不同在于,癌症手册弥补了癌症分子生物学与临床诊断与治疗之间的差距。
2 K) a* Y- `: k9 P- P涉及广泛的学科-从基本细胞生物学到所有主要器官和组织的系统肿瘤学-癌症手册的内容组织成六个主要部分:
) E1 W* S( H( E$ \0 B• 细胞和组织的分子基础
, r2 \& \4 K+ L" |+ C( R8 I• 癌症的原因和预防- x: I3 F% `! M- S+ @% W9 Y
• 诊断显象和影像-引导的乾涉# n3 k8 A' T+ Q% h$ h$ `
• 系统肿瘤学
9 M1 W( l" ]% u+ Q! {+ h• 人类癌症的预诊断模式) b, e! c6 E) @0 z1 Y# Z" b
• 人类癌症的治疗% x) ~; } ~" C# c& o9 f
# Z$ ~: C- ?( x+ N- e4 w6 `! c对于医学和生命科学学生以及所有在癌症领域和相关生物医学领域工作的科学工作者、临床医师和研究工作者来说,这本书是不可缺少的资源。& [( j* H& ?" S U/ l5 F
" ^. Q6 k8 F. l) F8 e
目录8 E$ Q/ F# a- C3 R5 U7 q) m
Section A - The Molecular Basis of Cell and Tissue Organization
) D6 I9 @8 I/ c1. Cell and Tissue Organisation2 d/ O( y1 S6 M* \* Q" C& g
2. Regulation of the Cell Cycle- J9 Z0 e, E0 I1 l7 L3 d
3. Overview of Oncogenesis
6 P8 ]( F2 ^& X/ u0 c. m4 L) @4. Inherited Predispositions to Cancer
! p& W% J. @: ?0 Z; O$ ~5. DNA Viruses; A: R# S( w- H% ~- V' \
6. RNA Viruses$ u1 I( i. r7 y; C' H+ r) C
7. Genetic Instability and DNA repair
( J; F/ O7 `: P8. Telomerase7 Q/ v4 K: \+ W
9. Apoptosis
, ^' l* k3 J# A10. Signalling by steroid receptors$ O. |! {; S% f0 {) h
11. Signalling by cytokines
2 a! n: \9 w! L( o12. Signalling by tyrosine kinases7 i' r% b4 \* {% H; V2 K0 I% N
13. Signalling by TGF beta! D' l7 g6 Q. R# {# P; s7 l
14. Wnt Signal Transduction& y7 L# l7 Q1 V+ y+ |1 z
15. Extracellular Matrix: the networking solution
" [' Q3 d+ l3 f3 F5 O- T0 n16. Invasion and Metastasis
1 `" y3 o5 }2 ^; T4 |! V( b17. Angiogenesis" ?" d/ P) a. c# f
18. Cell Proliferation in Carcinogenesis% f' @' ]* a5 s5 j/ e
Section B - The Causation and Prevention of Cancer
" b: Q5 S3 u* f! Q1. Identifying Cancer Causes through Epidemiology
& z! Q( l# S0 V! E0 R2. Mechanisms of Chemical Carcinogenesis( R3 D+ p6 {& F/ W7 C0 s& T; r7 W
3. The Formation of DNA Adducts
0 `5 y7 O: a* Q7 T9 X4. Physical Causes of Cancer
+ v, A h p( L5. Non-Genotoxic Causes of Cancer# b ~- `* y+ U' Q8 T
6. Infectious Agents and Cancer1 G1 H0 |0 J. k& L' `
7. Short-term Testing for Genotoxicity( Z& ^1 g/ O7 H3 A% f( q/ S
8. Cancer Bioassays for Pharmaceuticals a Regulatory Perspective& h( W; N( L J/ g$ ]2 D, Y! h9 }" ~
9. Molecular Epidemiology of Cancer
; q$ F" }" C( X: E+ B10. Dietary Genotoxins and Cancer
& ^+ D d% H$ O11. Tobacco Use and Cancer
; z( y8 E* |0 s( a12. Occupational Causes of Cancer$ r- o3 U/ W \6 Q
13. Anti-Genotoxins and Cancer% n, g) v! m% N3 P5 v. c5 m
14. Intervention and Chemoprevention
# o) q" X* A3 HSection C - Diagnostic Imaging and Image-Guided Intervention- |7 [( |, x% w) V
Part I- Imaging Modalities in Diagnosis and Monitoring y9 E3 e/ P8 g" q7 H! Z* o' Z
1. Plain Film Radiography
6 i: t1 {" l0 h! J& b% R! K5 J2. Computed Tomography" s" S. C) h7 G: h. S6 P
3. Ultrasound( U& o7 ~$ j7 X( m$ N% F: S) ?: {
4. Magnetic Resonance Imaging' S- _! F! x% X0 u3 z3 j/ g3 ]
5. Nuclear Medicine Studies
) n* ?/ N9 p+ e* f2 _6. Mammography
6 _2 I' U p3 n/ C/ }! e4 gPart II - Diagnostic and Therapeutic Interventional Procedures- U7 c) D6 G$ ?$ {( l+ F
1. Percutaneous Biopsy, M% e9 W9 {. o6 u9 }, Y) D1 Y- P
2. Transcatheter Therapy- l3 q" \3 Y% t. p' a, A
3. Direct Percutaneous Tumour Therapy
8 W; C- b0 j$ f- B& O/ b- u* sSection D - Systemic Oncology
2 A- s8 N5 t. O% b/ ~1 v8 l0 J1. Introduction to the Diagnosis of Cancer
5 H4 W, E! D- i0 H+ Z7 k) I2. Skin
; V: K9 z" q# M* Y- V& m3. Oral cavity & major and minor salivary glands1 Z b: }8 D3 t8 r% Q: N
4. Respiratory tract
- [5 q; ]$ J' Z4 c2 T5. Upper Gastrointestinal tract
9 K0 l' o* S' b" L" Y. x6. Lower gastrointestinal tract8 c! V8 O+ {; E$ w' n5 t
7. Liver, gall bladder and extrahepatic bile ducts./ p7 }9 A$ \0 d6 Z- p% ]; _
8. Pancreas
8 |+ Y; o% S3 S8 A2 J: X/ P9. Endocrine organs
7 b1 Y, Y8 ]* q3 B10. Breast
' t. }+ B# r' l11. Female reproductive system
( }! U0 ^' c6 W! ]# }3 c12. Urinary tract3 x: l& a7 r$ e! d) U3 `
13. Male reproductive system% ]! [* W8 p% {0 V! v o/ C
14. Lymph nodes, spleen and bone marrow.
0 Q# A3 o# w* ~( Y- R% V15. Bones and joints.
6 o9 ]4 C& p5 L4 A$ Z* c16. Soft Tissues9 {) I8 |! @! L0 M% N8 j
17. Pleura and peritoneum$ j) I/ \" w, a* x9 d+ J! J
18. Heart; }& O6 E& n; z. O( \' a& x8 A G k
19. Neuromuscular System z+ Y# _6 A/ c4 ?4 ?" e# S @8 \
20. Eye and ocular adnexa0 O$ n# v1 g+ K }6 l- M3 I* Y4 u9 ~" n) i
21. Ear
% J' k5 T3 e- p( n' ^9 B" lAppendum. Myeloid Leukemias and related Neoplasms
$ H! E2 N, H B/ a8 kSection E - Pre-clinical Models of Human Cancer! Y$ p5 N1 _, f; @' u2 L, V
1. Advantages and limitations of models for human cancer
; h l+ o# m l# i2. Basic Tissue Culture
: z( f, I2 S; @! O5 h) k) k7 i3. Transgenic technology in the study of oncogenes and Tumor Suppressor Genes
9 u& Z* f& ?( x0 k( `9 K4. Gene knockouts
( W9 N# s- R8 e2 K; [5. Human tumours in animal hosts
^2 H; B3 u# n% S6. Mammary tumour induction in animals as a model for human breast cancer
6 s! ? W6 x: m; Y T/ K7. Mathematical models in cancer research
; W7 A6 A; D6 F8. Models for tumour growth and differentiation3 l* z* j' {% A, w! N
9. Angiogenesis models
: O7 l- j% {3 Q10. Models for tumour cell adhesion and invasion! ~8 W# w" \1 b3 _! V4 X
11. Tumour metastasis models
; h: t. O: n( [& A$ M6 W* }2 t12. Models for tumour cell-endothelial cell interactions
& \3 s" G( |6 R2 l7 l& ~* h13. Modelling Tumor Tissue Interactives8 B* F3 R9 H6 @! g1 d# a
14. Models for drug development and drug resistance
+ ^3 e+ y5 M# f& j* H+ Y% f3 w15. Models for immunotherapy and cancer vaccines' ]* _! O. I: W
16. Gene therapy models$ G0 c7 [+ e' ]; ?8 A6 |0 x2 a
17. Models for epithelial carcinomas
/ h) f# u5 l; D3 M$ R- i18. Models for haematological malignancies- O" a* ?/ g7 X
19. Models for melanomas and sarcomas; Y9 Z, ?$ N/ m2 |$ T, B7 w9 O" m
20. Models for CNS malignancies# u1 H. X# z( a: a: i/ S {
21. Models for endocrine cancer% M4 z3 Q; h3 P9 b1 {9 N
Section F - The Treatment of Human Cancer
6 P8 n0 V% X, [- b4 W* z7 [1. Mechanisms of action of cancer chemotherapeutic agents: j3 N. [4 a8 Z! q6 |4 N) ~* z8 k7 }
2. Drug Resistance & Reversal/ Z" K F. Z2 L# i/ x
3. Molecular mechanisms of radiotherapy
$ R# U$ m* g v9 L4. Antibodies and recombinant cytokines3 z: O. g1 }6 i3 }; C$ W
5. Genetic and Cellular Vaccines
0 e# q2 I$ l- q2 M6. Differentiation Therapy" @$ A; n( R H$ H$ E- R
7. Chemoprevention
$ G' O7 V4 x4 [# g, L! [9 o8. Antisense & ribozyme therapy
4 w. p/ `: f$ i. y( X, m! G8 U9. Hormonal Therapy
" g' } i0 C4 E/ R10. Antiangiogenic Therapy" d! `* i/ |! A7 E8 ~ D
11. Targeting the Extracellular Matrix! k& C/ Q1 n( q
12. Growth Factor Receptor Blockade. K, Z# h% E* w4 W! P/ U; S
13. Signal& A' R; y# V3 K+ }5 i$ F
1 M% V$ G1 W5 Q[ 本帖最后由 清风明月008 于 2007-8-12 10:32 编辑 ] |
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